Part 1 ("The Disappearance") details Kenley Matheson's strange disappearance from Acadia University (Wolfville, Nova Scotia) on 21 September 1992, from his arrival on campus to the day he went missing. Part 2 ("The Investigation") traces the initial investigation by the Wolfville Police Department and presents the prevalent theories at that time regarding Kenley's disappearance.

Part 3 ("The Serial Killer") is centered around the theory that Kenley Matheson met suspected serial killer Andrew Paul Johnson the weekend before he went missing. Part 4 ("The Seeker") goes back in time and traces the Kenley's story from his Cape Breton youth to his motorcycle "gap years" prior to enrolling at Acadia University.

Part 5 ("The Superb Meteor") explores the theory that Kenley might still be alive and investigates into several of the most credible sightings of him that have taken place over the years. In Part 6 ("The Backpack") a new version of events emerges over the course of production that further suggests foul play and seems to implicate Kenley's two closest Acadia friends...

Part 7 ("The Secret") takes us into real time with Kenley's family as a twenty-four-year-old family secret about his murder comes out five years into filming. New details emerge about Kenley's potential killer and as RCMP ineptitude pursuing this new person of interest becomes more and more apparent.

Part 9 ("The Obfuscator") investigates the potential killer's involvement in Kenley's disappearance through interviews with the POI's family members and the help of a forensic hypnotist. In Part 10 ("The Missing Link") Kenley's mother goes to meet this new person of interest, followed by an interview with the suspect's sister, who links her sibling directly with Kenley's disappearance.