Wracked with grief over Ellie's death, Rowan is out of control and unfit to perform surgeries; her paranoia that someone is following her is proven true; in New Orleans, Deirdre and her mysterious companion Lasher work together to draw Rowan home.

In the aftermath of Deirdre's grisly death, Rowan searches for safety in a strange city; Sip provides Rowan with a safe house while he investigates Deirdre's murder; Lasher makes contact with Rowan, but not in the way one might expect.

At Deirdre's funeral, Rowan is plunged into the world of the infamous Mayfair family; Uncle Cortland and Aunt Carlotta present diverging views on Lasher; Rowan must choose whom to trust and face the dire consequences; Sip identifies Deirdre's killer.

Trapped in the First Street House, Rowan and Sip must confront its many mysteries in order to escape; Rowan grapples with an inconceivable offer; Sip's sister Odette makes a horrifying discovery.

Desperate to relinquish Lasher, Rowan reaches out to her extended Mayfair family for help; Rowan must trust their unique process, a sacred ritual; Sip's search for answers takes him back to the Talamasca.