After a sudden fall from grace, arrogant, high-flying heart surgeon Dr. Hugh Knight is forced to leave his hedonistic, inner city life when is forced to take the position of local GP in the small country town where he was born.

Hugh wakes up in a house he doesn't recognize, littered with the remnants of a big night and Aoife face down on the floor. Thankfully, she's alive. Upon seeing his hungover state, Penny, however, is not amused and orders him to provide yet another urine sample. Hugh extracts one from a young patient in return for a doctor's note - but unfortunately, it tests positive for cannabis. Hugh's mood is boosted by a call from a Sydney surgeon in need of his help, but the respite is only fleeting as a 16-year-old pinned under a tractor tragically bleeds to death on Hugh's watch. This moment, along with a D&M with his old friend, Joey , who is facing a potential cancer diagnosis forces Hugh to reflect on his life choices. Meanwhile, tensions rise in the Knight family, as a family dinner sparks old flames and tests new dynamics. In an effort to do something right, Hugh bails up his schoolfriend-turned-mining-magnate 'Big Nathan' for $40K and hands it over to Penny for much needed MRI machine, to her delight and great surprise. Giving him a second chance, Penny decides to not test another urine sample.

Charlie and Matt host a wild B&S Ball at their brewery, meanwhile Hugh finds a surprising test subject for his new artificial heart.

When Hugh is sued for malpractice he must travel back to Sydney to defend himself. He drags Matt along with him in an attempt to bond with his brother but it backfires when Matt is found in a comprising position with another woman. Charlie is pushed to the limit by Meryl and takes revenge with a goat and Penny is put in a tricky position while safeguarding Hugh's complicated life. In misguided honesty Matt 'comes clean' with Charlie - while Joey delivers a shocking and life changing revelation to Hugh. In a last ditch effort to pacify Henry's threats of suing, Hugh returns to Sydney with Ajax in tow and offers up his ocean view bachelor pad as compensation - big city life is getting further and further away.

Hugh becomes the town hero after footage goes viral of him saving a promising young footballer from a booby trapped paddock-turned-minefield. He is swiftly brought back down to reality after being accosted by Ajax for not being able to fix the footballer's hand, and also by Meryl for letting Ajax search the minefield for his friend's fingers. Matt, Charlie, Hugh, Aoife, Joey and Tugger all blow off some steam and get back to basics - a country style lock in with plenty of booze. Charlie has a revelatory kiss, and tries to re-energise her relationship with Matt, only to collapse in pain. Hugh gains a deeper understanding of Penny and what it means to be a parent, while she grieves the anniversary of her husband's death. With Penny AWOL, Hugh must operate on Charlie's ectopic pregnancy. As she and Matt grow closer, Hugh turns to Aoife for some distraction. Hugh-style.

When a brawl at the local pub turns fatal, Hugh learns that they can't save them all. But things only get worse when the transplant team arrives from Sydney, and it's led by Hugh's ex-colleague and long term rival, Daniel. Hugh desperately attempts to hide the fact that he is now working as a country GP, but it's not long before Daniel has exposed him. In the process, Hugh ridicules Whyhope Hospital, and inadvertently offends Penny, Betty and Ken. When Hugh and Penny go to give vaccinations to a rural family they have a run-in with Craig - a farmer with a shotgun. Forced to talk his way out, Hugh is given a fast lesson in what's involved in being a country doctor. Which is lucky, for when Hugh realises that Betty's friend has a subdural haemorrhage, it calls for some low-tech fast thinking, and he drills a bore hole into the man's skull to reduce the pressure. Meanwhile Charlie and Matt are dealing with the aftermath of Charlie's ectopic pregnancy, and Meryl begins on a series of well meaning, but misguided attempts to comfort her. The family gets together for Ajax's sixteenth birthday dinner, complete with an outlandish present from Hugh: a Ducati. During dinner Hugh is outed by a tweet from Ken, and the whole family discover why he is really back in Whyhope.