A group of seemingly unconnected characters are caught up in a paranoid schizophrenic's path of death and destruction. Nadine, a prostitute trying to make her way through school, comes across the seemingly innocent and naive Lucille asleep in a run-down alley one morning. Nadine tries to help her out by introducing her to a nightclub owner who leads a double life as a pimp. Neither realizes that Lucille harbors a deadly secret. Jake Van Sant, local crime boss and father to Lucille, believes she is plagued with a mythological curse that changes the fate of anyone who shows her kindness. Heeding the warnings of his psychic, Van Sant sends his top hit men on a mission to track her down before she makes her way back home. As the body count adds up, the truth behind Lucille's curse begins to unravel, with deadly consequences for all.