James Sharpe

Tom (Aziz Ansari) tries to get back at Ron (Nick Offerman) by going out on a date with Ron's ex-wife Tammy (guest star Megan Mullally), while Leslie (Amy Poehler) tries to protect Ron from falling prey to her charms. Meanwhile, April (Aubrey Plaza) is assigned to work with Chris (Rob Lowe). Rashida Jones, Chris Pratt, Adam Scott, Jim O'Heir and Retta also star.

After a suspected serial killer wakes up from a coma, the BAU reopens the case and uses brain fingerprinting to determine if he really doesn't remember the crimes that had been committed four years earlier in Roanoke, Virginia.

As Mack and Tiffy prepare to leave the Unit the rest of the team travels to Pakistan to try to stop terrorists from unleashing a deadly smallpox epidemic.

Nick represents Dale, a young boy undergoing chemotherapy for leukemia, who's only chance for survival is a bone marrow transplant.

Vaughn and Sydney search for the key to open the Rambaldi box.

Underlay might get the quarantine he has requested when Russell discovers that escaped laboratory animals may be responsible for a deadly flu virus that has spread throughout Homestead.