As the Fringe team tirelessly explores a mysterious incident involving a man whose strange and creepy dreams project nightmarish events, Agent Broyles has a meeting with Nina Sharp.
Clark and Lana each try to kill Chloe for unknown reasons after they receive a mysterious e-mail from the Summerholt Institute. Clark must discover the source of these e-mails after Chloe reveals she has uncovered proof that the laboratory is involved in mind-control research--and someone wants to prevent her from writing an exposé. Meanwhile, Lana rents the apartment above The Talon to Adam (recurring guest star Ian Somerhalder), even though she feels he is hiding something dangerous about his past.
Clark learns that John Jones was shot while working as a police officer; Lana tells Tess that Lex isn't the man she thinks he is, forcing Tess to re-evaluate her position as head of Luthercorp.
Peter Farragut, Sarah Jordan and Dr. Kyle Sommer go to a mysterious island to investigate an unknown pathogen that killed everyone, except Leila, aboard the Mist of Avalon.
Jordan discovers Alan, Peter’s brother, is a member of Brother Michael’s cult, but despite Alan’s warnings she and Peter refuse to leave the Abbey and continue to investigate how Soren became infected.