Jake is called upon to negotiate a hostage situation with a jewel thief, only to discover that the culprit seems to be a familiar face. Amy and Gina help Charles with the high demands of his new food truck, and Holt panics when a member of the Police Commissioner selection committee decides to interview Hitchcock about Holt.
With the help of Special Agent Genny Shaw (guest star Tina Majorino), the Jeffersonian team identifies the remains of a discount shopper and “extreme couponer” who was dragged along the road by an 18-wheeler. Meanwhile, Brennan is adjusting to her first day back at work after giving birth, and Cam disapproves of her daughter’s romance with intern Finn Abernathy (guest star Luke Kleintank).
The team's holiday plans are put on hold when the murder investigation of a Navy veteran includes the discovery of a newborn baby who has no identification and no apparent ties to a family.
Spencer takes her anger out on Mona; Hanna devises a plan to bring Caleb and his father back together; Aria spends more time with Wes; Emily and Jason try to determine what happened during Ali's vacation in Cape May.
While working at their non-profit clinic three hours outside of Atlanta, Nic and Mina treat a patient with a failing heart VAD, forcing them to find a new battery in time to save her life. Conrad gets a call from a previous patent in crisis after being sued by Red Rock for medical expenses he can’t afford. Meanwhile, Devon’s VIP patient, Nadine, returns to the ER.
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