Noel Conlon

Tension builds as Mel subjects Niles to social humiliation before she will grant him a divorce.

When Henry (guest star Howard Hesseman) experiences a seizure but is not aware of it while it’s happening, House takes on the case. The team’s differential diagnosis points to a bacterial infection, but Henry suffers a heart attack before the treatment for his infection is able to work, prompting the need for a heart transplant. Racing to find a heart donor in time to treat Henry before the infection kills him, House finds an organ donor who’s been declared unfit due to a mysterious illness.

A whacked-out Grace (Debra Messing) is wracked with guilt over the death of a high school classmate whom she once tormented, so she drags Will (Eric McCormack) along to the funeral - and gets the surprise of her life - while Will offers a sympathetic shoulder to a handsome grieving relative (guest star Todd Stashwick). Elsewhere, an ecstatic Jack (Sean Hayes) asks Karen (Megan Mullally) to accompany him when he is nominated for a lower Manhattan, non-transgender Equity Waiver gay cabaret award.

Eugene defends a man who is accused of murdering his little daughter. Ellenor finds herself facing a lawyer with whom she has a long-standing story. He had harassed her, and when she faced him, he completely denied it.

Nick defends a sexually abused teenage boy who wants to protect his father from being implicated in the crime, even though it appears that his father was the abuser.

On a train trip, the Harts investigate an undercover police officer's death; guest Carol Lynley.