Timothy Landfield

Brennan and Booth investigate the site of a train wreck where the bodies of a senator and a high-profile businessman are found within the wreckage. The businessman's body is found in a car on the train tracks, and at first glance, it is an apparent suicide. While investigating a possible connection between the two victims, Brennan and her team discover the businessman is still alive, but severely injured, at a local hospital, and the body at the scene is someone else. As the clues begin to unravel, the investigation gets more complicated when details of the man's private life are revealed, leading Brennan and Booth to a private detective who may hold key information. Meanwhile, Brennan is introduced to Dr. Camille Saroyan, a first-rate pathologist who has been hired as the head of forensics at the Jeffersonian, and more importantly, Brennan's boss. It doesn't take long for Brennan to figure out "Cam" is a little too familiar with Booth and that they share something of a past. Also, Booth encourages Brennan to visit her mother's gravesite for the first time.

Grissom and Warrick investigate the case of young man found dead in the desert, while Catherine and Nick look into the murder of a school dean.

Baby TJ's christening turns grim when a body is discovered in the church. Jane almost abuses her power in order to protect her brother Tommy (recurring guest star Colin Egglesfield) when Lydia's fiancé, Stuart Stawbridge (guest star Jareb Dauplaise – Mad Men) threatens to take custody of TJ, and budget cuts cause tensions to run high around the department.

Sharona's sister, Gail (Amy Sedaris), is starring in a play bound for New York, and Monk and Sharona are in the audience. During a scene, Gail uses a fake knife to "stab" another actor. The actor gasps and wheezes before falling to the floor -- but then doesn't get up. A doctor rushes onstage from the audience and determines that the actor was stabbed in the chest. Gail is immediately arrested and charged with murder. As if things weren't stressful enough for Sharona, her mother arrives for a visit. Sharona tries to push aside her feelings to prepare her mother for the news of Gail's arrest. As expected, Mrs. Fleming is beside herself -- her daughter is being accused of murder! She asks Monk and Sharona to help clear her daughter's name.

Sloane is told that Sydney is the SD-6 mole, putting her life in danger; Dixon is shot; Will thinks Kate Jones' pin is the key to some unexpected information.