Danny and Baez investigate a murder attempt against a celebrated fertility doctor with a seemingly pristine reputation. Also, Eddie is called to intervene in a Reagan family matter involving Danny’s boys; Erin helps Anthony find justice after a date night goes wrong; and Frank ties up loose ends with an old friend.
A patient's paranoia has an adverse medical effect.
In the sixth season finale, a new lead in a cold case requires Lisbon to delay her plans to leave for Washington, D.C. with Marcus Pike, giving Jane time to finally come to terms with his feelings for her and decide on a course of action.
When an ER physician is gunned down in the street, Castle and Beckett soon discover that the victim was a mob doctor to a Mafia family run by an old friend of Castle's. Also, against this backdrop of Christmas, Esposito and Lanie reach a defining moment in their relationship.
When two casualties resemble the M.O. of the most notorious killer in Italian history, the International Response Team is called to investigate.
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