When faced with treating a man whose cheek is about to pop due to a 4lb tumor, Dr. Panossian worries it could become a deadly situation. A woman who's lower lip won’t stop growing turns to Dr. Rovelo for help.

Dr. Roostaeian wants to help a young woman living with the largest birthmark he's ever seen, however, surgery could be life-threatening. After being hit by a drunk driver, Dr. Rovelo's patient hasn't been able to close his mouth.