Twenty one- year-old beautyholic and drama student Gary Thompson meets 47-year-old Reggie Bibbs from Houston; Reggie suffers from neurofibromatosis, a condition where tumours grow all over the body.

Forty three-year-old travel agent and beauty addict Amanda Hughes meets 46-year-old civil servant Debbie Hanson; Debbie introduces Amanda to her family and explains what it is like living with a facial disfigurement.

21 year old glamour model Holly Kent meets 27 year old Nelly Shaheen who was born with Harlequin Ichythiosis, a rare skin condition, which makes Nelly look like a burns victim.

Hairdresser and beauty-obsessive Corinne Harrison meets teacher Simon Moore.