Common Side Effects
TV Show · Animation · Thriller

Former classmates Marshall and Frances uncover a sinister conspiracy to destroy a mushroom that can cure all the world's diseases.

2025 · 21m
  • 14+
Starring Joseph Lee Anderson, Mike Judge, Martha Kelly

Season 1

  • EPISODE 1
    Pilot
    Marshall Cuso shows up in NYC with a mushroom that can cure any disease or injury. His old classmate, Frances, meets him by chance, but keeps secret that she works for Reutical, a big pharmaceutical company.
    20m
  • EPISODE 2
    Lakeshore Limited
    Marshall is on the run, trying to flee New York. Frances confides to her boss Rick about the mushroom. Rick sends her to Marshall’s farm to get more but the situation gets out of hand.
    21m
  • EPISODE 3
    Hildy
    Marshall seeks advice from his old professor/mentor, Hildy. Copano and Harrington are drawn further into the mystery of the mushrooms obtained at the raid. Frances has gone to Geneva with her boyfriend Nick (and Rick), but can’t resist the call of the mushroom.
    21m
  • EPISODE 4
    Dumpsite
    Marshall buys a plot of land near a chemical waste site with a plan to grow more mushrooms. Meanwhile, Frances rushes home from Europe after a huge development. Copano and Harrington investigate a connection between Marshall and Frances.
    21m
  • EPISODE 5
    Star-Tel-Lite
    Frances and Marshall attempt to grow the last of their mushroom supply, hoping their plan works. Copano and Harrington, surveilling Frances and Marshall, run into danger when confronted by a neighboring BMX gang.
    21m
  • EPISODE 6
    In the System
    Marshall arrives in jail and learns that some very important people refuse to let him out, while danger lurks around every corner. Frances makes a fateful decision. Copano and Harrington pick up the pieces.
    21m

Related

Cast & Crew

  • Joseph Lee Anderson
    Copano
  • Mike Judge
    Rick Kruger
  • Martha Kelly
    Harrington
  • D‌K
    David King
    Marshall
  • Emily Pendergast
    Frances
  • Greg Daniels
    Executive Producer
  • Steve Hely
    Creator

About

Common Side Effects

Animation

Former classmates Marshall and Frances uncover a sinister conspiracy to destroy a mushroom that can cure all the world's diseases.

14+

COMMON SENSE

Drugs, medicinal mushrooms, conspiracies in animated comedy.

Information

Studio
Discovery Global Adult Animation
Released
2025
Rated
TV-MA
Region of Origin
United States
© ADULT SWIM 2023 The Cartoon Network, Inc. A WarnerMedia Company. All Rights Reserved.

Languages

Original Audio
English (United States)
Audio

English (United States) (⁨Dolby 5.1⁩, AAC)

Subtitles

English (United States) (CC)

Accessibility

Closed captions (CC) refer to subtitles in the available language with the addition of relevant non-dialogue information.
  • Español (México)
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Select a country or region

Africa, Middle East, and India

  • Armenia
  • Azerbaijan
  • Bahrain
  • Botswana
  • Brunei Darussalam
  • Cape Verde
  • Egypt
  • Eswatini
  • Gambia
  • Ghana
  • Guinea-Bissau
  • India
  • Israel
  • Jordan
  • Lebanon
  • Mauritius
  • Mozambique
  • Namibia
  • Niger (English)
  • Oman
  • Qatar
  • Saudi Arabia
  • South Africa
  • Sri Lanka
  • Tajikistan
  • Turkmenistan
  • Uganda
  • United Arab Emirates
  • Zimbabwe

Asia Pacific

  • Australia
  • Cambodia
  • Fiji
  • 香港 (廣東話–繁體)
  • Indonesia (English)
  • 日本
  • Lao People's Democratic Republic
  • 澳門 (廣東話–繁體)
  • Malaysia (English)
  • Micronesia, Federated States of
  • Mongolia
  • New Zealand
  • Philippines
  • Singapore
  • 대한민국
  • 台灣
  • Thailand
  • Turkmenistan
  • Vietnam

Europe

  • Armenia
  • Österreich
  • Belarus
  • Belgium
  • Bulgaria
  • Cyprus
  • Czechia
  • Denmark
  • Estonia
  • Finland
  • France (Français)
  • Deutschland
  • Greece
  • Hungary
  • Ireland
  • Italia
  • Latvia
  • Lithuania
  • Luxembourg (English)
  • Malta
  • Moldova, Republic Of
  • Nederland
  • Norway
  • Poland
  • Portugal (Português)
  • Россия
  • Slovakia
  • Slovenia
  • España
  • Sverige
  • Schweiz
  • Türkiye (English)
  • Ukraine
  • United Kingdom

Latin America and the Caribbean

  • Anguilla
  • Antigua and Barbuda
  • Argentina (Español)
  • Bahamas
  • Belize
  • Bermuda
  • Bolivia (Español)
  • Brasil
  • Virgin Islands, British
  • Cayman Islands
  • Chile (Español)
  • Colombia (Español)
  • Costa Rica (Español)
  • Dominica
  • República Dominicana
  • Ecuador (Español)
  • El Salvador (Español)
  • Grenada
  • Guatemala (Español)
  • Honduras (Español)
  • México
  • Nicaragua (Español)
  • Panamá
  • Paraguay (Español)
  • Perú
  • St. Kitts and Nevis
  • Trinidad and Tobago
  • Venezuela (Español)

The United States and Canada

  • Canada (English)
  • Canada (Français)
  • United States
  • Estados Unidos (Español México)