The Magnolia Plantation in Derry, Louisiana, which dates back to the early 1800's, entices the Ghost Brothers to investigate claims of deceased slaves still practicing voodoo in the afterlife.

The Ghost Brothers travel to Monticello, Arkansas to investigate the Allen House, which has claims of doppelgangers and apparitions connected to a love triangle and a jilted woman's suicide that took place in the house in 1949.

Prospect Place, in Trinway, Ohio, was once a stop on the Underground Railroad. This historic mansion lures the Ghost Brothers to find out if an evil entity and other unsettled spirits that date back to the civil war era, still reside on the property.

The Delta Queen, a historic riverboat, was relocated to Houma, LA for extensive renovations, setting off paranormal activity. The Ghost Brothers' mission is to find out what spirit is behind the frightening phenomena.

The Ghost Brothers travel to The Magnolia Hotel in Seguin, Texas. Their mission is to find out if murders and suicides that occurred at the hotel are linked to a continued presence of threatening paranormal activity.

The Ghost Brothers head to Washington, Georgia to try to solve the mysterious hauntings of The Fitzpatrick Hotel, which was built on a gravesite. Some believe that reports of multiple female spirits residing at the hotel are tied to a tragic death.