Since childhood, Nelly and Fabiola Calle have wanted to be pop music stars. Guided by their grandmother and supported by their mother, sisters and selfless benefactors, they persevere with tenacity, talent and a unique repertoire. The road to success is full of obstacles due to unexpected enemies, irresponsible family members, ungrateful lovers and a musical style deemed not attractive enough for traditional media. However, the Hermanitas Calle are ready to face and overcome any difficulty.