Samantha Newly, the young vice president of a real-estate firm, is forced to start life over after a horrific hit-and-run accident leaves her with amnesia. As she reconnects with acquaintances in her old life, however, Sam is disconcerted to discover that she apparently was a self-centered, narcissistic witch with no successful relationships to speak of. But she wants to be good now, so she sets out to make amends with friends and family, including off-again, on-again girlfriend to roommate and ex-boyfriend Todd.