After winning a contest for "Gritty Kitty Litter", Stimpy leaves Ren to become a Hollywood star. Despite his fame and fortune, Stimpy realizes he misses Ren and returns.

Ren dreams that he is a brave outlaw who robs from the rich and Stimpy is a damsel in distress. / When Ren gets sick, Stimpy acts as nurse and dedicates himself to curing his friend.

Commander Hoek and Cadet Stimpy, on a 36 year mission to the Crab Nebula, go crazy from boredom. Stimpy guards the mysterious History Erase Button. / Penniless and hungry, Ren and Stimpy get jobs. Stimpy promises a family he can catch a troublesome mouse that is actually Ren in disguise.

Ren and Stimpy get jobs as fire dogs and save a cast full of characters during a 40-story building fire. / After reading the story of the "Littlest Giant," Stimpy runs away. He arrives in Thumbsville during a terrible drought, saves the town with his tears and makes a new friend.

Commander Hoek and Cadet Stimpy's rocket hurtles out of control and leaves them marooned on an eerie uncharted planet, where they attempt to find food and avoid the hideous Braniac men. / Ren and Stimpy host a nature show and travel to an island to see how different species adapt to their surroundings.

Ren and Stimpy pass through a black hole, mutate in their strange surroundings and find a mountain of missing left socks. / Stimpy invents a happy helmet that pushes the naturally angry Ren past the happy limit into madness. Stimpy plays his favorite song, "Happy Happy Joy Joy."