In 1987 a violent rapist haunts the Toronto area and soon his crimes escalate. Police, looking for two male suspects, are shocked to find the trail leads to a charming newlywed couple who rape, torture and kill young girls in their love nest.

In 1997, authorities from Reno to Sacramento are on the lookout for a man and woman who are kidnapping women and sexually assaulting them in their minivan. Fueled by methamphetamine and a pathological drive to satisfy their deviant urges, no one is safe.

A retired couple is viciously stabbed to death in their Virginia home, and police work diligently to investigate every lead possible. Soon they find themselves questioning the couple's daughter and her boyfriend.

In the late 90s, a number of young women go missing in New Mexico. Some return and some don't. The ones who do are plagued by nightmarish visions and lost memories. Authorities discover a sadistic couple has set up a chamber of horrors in their home.

In 1985, police in South San Francisco, California respond to a simple shoplifting incident. Within hours, they discover a connection between two male suspects and a list of missing people that spans more than a year.

He was the son of a convicted murderer, and from a young age, seemed destined to follow in his father's footsteps. She grew up affluent and spoiled. When they meet in 1978, what follows is one of the most shocking crime sprees of the twentieth century.