While returning an injured Klingon to his people, the Enterprise is intercepted by a rogue race of aliens called the Suliban.

The Enterprise is on its first deep space mission, when a villainous race called the Suliban kidnap the Klingon they are transporting, forcing Archer to make a detour.

The crew finds 15 humanoid corpses that appear to have been part of a horrific scientific experiment.

While stranded on an uninhabited planet, Trip, Mayweather, and T'Pol are overcome by paranoid fantasies, caused by a hallucinogenic released by flowers. Archer must save them before they turn on each other.

Trip becomes pregnant with an alien baby, after being dispatched to an alien ship where he has a close encounter with one of the ship's engineers.

When the crew alters course to explore a deserted Earth colony called Terra Nova, they come face-to-face with the colony's human descendants who have evolved in a surprising manner.