Following the assassination of Bobby Kennedy, Jackie defies public opinion and marries Greek shipping magnate Aristotle Onassis. Ted Kennedy is pressured to replace his fallen brother and continue the legacy of “Camelot” by running for the White House himself.

The Kennedy family is shaken to its core when Ted’s car accident at Chappaquiddick results in the death of his female companion. Jackie returns from Greece – over the objections of Onassis – to help the Kennedys, only to find herself drawn into their attempt to save Ted’s career by evading justice.

The Chappaquiddick disaster is resolved, though a permanent cloud hangs over Ted’s public life and his conscience. Jackie’s marriage to Onassis ends when the death of his son convinces him that she’s the bearer of the “Kennedy curse”. She returns with her children to live in New York, but her relationship with JFK Jr is strained as he chafes under the burden of his father’s name. Ted falls deeper into alcoholism and depression when his son suffers a catastrophic illness.

Ted runs for President in 1980, but his campaign is a failure. His marriage ends in divorce. Jackie urges him to reform his personal life. She finds happiness with a new companion. But that happiness is cut short when she dies at the age of 64. JFK Jr contemplates a run for office, but he’s killed in a plane crash that ends forever the legacy of “Camelot”.