The first episode in which Charlie – a baseball player with anger issues turned anger management therapist – decides to return to therapy after a bad run-in with his ex wife’s new boyfriend. The only problem is he just happens to be sleeping with the one therapist he trusts: his best friend, Kate.

The new "evolved" Charlie has to deal with a ghost from his old carousing, baseball-playing days when a unattractive woman he slept with just to break a batting slump shows up as a new patient in group therapy.

Charlie challenges his group to do thirty-six hours of sleep deprivation therapy so that their "inhibitions come down and the truth comes out" - except the result turns out to be the exact opposite.

A long-standing rivalry over who's a better therapist leads to war when Kate steals Patrick, one of Charlie's group patients.

Inflamed by Kate's comment that he's only "nouveau smart", Charlie starts covertly dating a brilliant coffee-shop barista.  The only problem is that the woman is turned on by sex where there's a chance of getting caught -- and she's Kate's patient.

Charlie and his ex, Jennifer, are having an issue with how Charlie still tries to manage her life when Cleo - one of Charlie’s patients from his prison anger therapy group – shows up on his doorstep, fresh out on parole. Jennifer decides to get back at Charlie by dating the ex-con.