Dr. Ann Burgess, a psychiatric nurse and professor, gets a call from the FBI that results in her participation in a new task force aimed at catching serial predators, she is thrust into an active investigation involving the assaults of over 20 women.

Ann dives deeper into the minds of serial killers, while balancing her life as a mother of four, as the Behavior Science Unit races to prove the success of profiling.

Ann publishes her groundbreaking study and serial crimes go down; but, she quickly comes to realise that there is never time to rest.