Nurse-out-of-water Hayley joins the fast-paced team of nurses and pilots at SkyMed, flying air ambulances and saving lives in rugged Northern Manitoba.

When a guilt-ridden Lexi finally goes flight line, she locks horns with training captain Bodie, while Crystal tries to get to the bottom of what Jeremy's been smuggling and how it's connected to Wheezer's crash.

The investigation into Wheezer's crash puts Lexi in the hot seat; a wildfire threatens Crystal's community, a look at whether she will cross the line to save a patient's life.