Six undercover participants from a variety of backgrounds are followed on the streets and in jail as they provide a firsthand look into how drug cartels have infiltrated America's heartland.

Charlie almost blows his cover and suspicions around him continue to grow; on the inside, Jenn struggles to connect with her fellow inmates.

Jackie meets a local Bonnie and Clyde, but Richie might blow her cover; Charlie is helped out by a raid; Jenn starts to bond with the women in her pod.

Charlie seizes an opportunity to get closer to his cellmates; the narcotics unit raids the residence of one of the largest drug traffickers in Kentucky; Jackie finds an unlikely lead for her investigation; Jenn passes valuable info on to Alexis.

Charlie comes face-to-face with a loaded needle during his initiation with the other inmates; Jenn learns how some of her cellmates smuggle drugs into jail; Jackie discovers a hot spot for cartel activity.