First-year surgical intern Meredith Grey begins her first day in the demanding residency program at Seattle Grace Hospital.
A young woman clings to life after a brutal attack, leaving the surgical staff optimistic. Meredith puts her career on the line to save a newborn in the hospital nursery.
The interns compete to treat severe injuries as patients from the annual bike-messenger race fill the emergency room. Christina and Izzie face a difficult situation with a brain dead patient.
Cristina treats a former Seattle Grace scrub nurse and is forever changed. Izzie's past comes back to haunt her and makes a case difficult.
Meredith thinks she may have made a mistake during surgery, endangering her career. Nothing goes as planned when Izzie throws a party for her new boyfriend.
Bailey interferes in Meredith and Derek's relationship. Alex works hard to gain the trust of a shy patient with a gargantuan tumour.
Dr. Meredith Grey
Dr. Alex Karev
Dr. Miranda Bailey
Dr. Derek Shepherd
Dr. Cristina Yang
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