When several prostitutes turn up dead near the Genessee River Rochester police conclude they're facing a serial killer. Investigators discover that the perpetrator returns to the bodies after the kill. Can they catch him before he strikes again?

Women are mysteriously disappearing from the streets of Philadelphia. Then Josefina Rivera, a prostitute who's been missing tells police that she's been held captive in the basement of a madman. Police descend on the house and make a shocking discovery.

When teenager Lynette Ledford is found naked a strangled to death, Los Angles police determine they're dealing with two sexually motivated killers. Police then uncover the suspects' van and find chilling evidence killers' reign of terror.

New Jersey police investigating a series of mob murders discover the victims are connected to one man, a coldblooded killer named Richard Kuklinski. Can undercover agent Dominick Parlifone infiltrate Kuklinski's circle and bring him to justice?

Police are shocked when Savannah local Milton Bradley is found brutally murdered. They soon discover he's the victim of a ruthless killer who preys on gay men. The FBI must track this transient hustler and catch him before he strikes again.

When healthy patients in New Jersey hospitals die of mysterious causes doctors are baffled. An investigation reveals they were victims of a sinister poisoning spree. Officials hone in on a hospital employee with a questionable record and a troubled past.