Thanks to a recent split from his ex-wife, Mackenzie (Jenn Lyon), self-made businessman Saint George (George Lopez) is reluctantly back on the dating scene and attempting to forge a relationship with his 11-year-old son, Harper (Kaden Gibson). But, more often than not, he's fielding wayward advice from his uncle Tio (Danny Trejo) and cousin Junior (David Zayas) and constant criticism from his overbearing mother, Alma (Olga Merediz). Add a boss (Diana Maria Riva) who makes it her job to sexually harass him, and George's love life doesn't stand much of a chance.