After suffering a personal tragedy, Bryan Mills embarks on a vengeful mission to bring down a ruthless cartel boss. Meanwhile, a covert U.S. intelligence team headed by Christina Hart recruits Bryan to become an operative.

Sidelined for weeks, Bryan finally gets an opportunity to work in the field. The ensuing mission unearths a sinister conspiracy surrounding a government official’s death. Meanwhile, Hart makes contact with a man from her past.

Bryan (Clive Standen) and team search for a suspected terrorist who has been taken, leading them to uncover a deeper plot within their own government. Christina (Jennifer Beals) receives troubling news and turns to Harry (Dominic Fumusa) for support. Asha (Brooklyn Sudano) expresses her concern over Bryan's fixation with Mejia (Romano Ozari).

Riley's (Jennifer Marsala) insistence to uncover the truth behind a fatal drug given to war vets results in her asset's child being taken. Bryan (Clive Standen) defies orders to rescue the girl and uncover the truth. When a break in at Asha's (Brooklyn Sudano) apartment leaves her shaken, a new neighbor is there to calm her nerves.

Christina (Jennifer Beals) orders the retrieval of sensitive documents in Zurich needed to prevent economic and political disaster. But the mission to break into a bank vault turns into a three way battle, and a race to escape safely. Meanwhile, Asha's (Brooklyn Sudano) trust in Elena (Layla Alizada) proves to be misplaced and leaves Bryan (Clive Standen) vulnerable.

The ODNI is asked to facilitate the defection of a Russian FSB agent, but the agent's pregnant girlfriend throws a curve in the team's plans. Meanwhile, Christina (Jennifer Beals) goes off the books to reveal a mole in the CIA, and John's (Gaius Charles) attempt to resolve his brother's problem with a local gang results in a spiritual crisis.