Sisters Prue and Piper Halliwell have recently moved into their dead grandmother's old victorian home in the San Francisco hills and when youngest, black-sheep sister Phoebe moves in with them, they discover they are descendants of an ancient Wiccan prophecy - the "Charmed Ones."

A good-looking man, Stefan actually kidnaps young, beautiful women and sucks their youth and beauty out of them to keep his own youth, now he has designs on Phoebe. Meanwhile, Prue lands a new job at an art house and also regrets sleeping with Trudeau and Piper questions whether her witchy powers make her a bad person.

The Halliwell sisters' long-lost father unexpectedly turns up and has intentions of getting the Book of Shadows out of their house; simultaneously, mysterious new neighbors move in across the street with intentions of their own.

After being killed by Asian gang thugs, Mark becomes a ghost whose soul is up for grabs depending upon if Yama, the demon who confiscates souls for hell gets him first. The sisters Haliwell can see Mark because of their powers where mere mortals can't; meanwhile, to earn extra money for a gift for Prue's birthday, Phoebe works as a physic at a local restaurant/bar.

After Piper and Phoebe cast a spell to dream up romantic interests, the dream sorcerer tries to get back at Prue after she rebuffs him at a nightclub.

Piper caters a wedding with Phoebe's help and discovers that Elliot, the groom under a spell by Jade, the bride and is forced to marry her instead of his true love, Allison. Jade is actually a hectate demon who must mate to continue the line of demons.