Brian's life turns extraordinary after taking a mysterious drug, NZT, that lets him access his full brain capacity; an NZT-related murder puts Brian on the FBI's radar.

Brian puts his new job at risk when he disregards orders to stay out of a renowned journalist's murder.

A retired FBI agent's murder is connected to the head of a notorious drug cartel; Brian and an old flame (Analeigh Tipton) reconnect.

Sen. Edward Morra's representative asks Brian to take the FBI's secret files on NZT; Harris makes a discovery that leaves her feeling conflicted.

Brian learns something about Rebecca's late father, but worries telling her about it would get him in trouble; Brian accidentally meddles in Rebecca's personal life.

Sen. Morra (Bradley Cooper) demands a high price for Brian's next inoculation to combat the side effects of NZT.