Mort gathers his children together to tell them something important; they fear he has cancer.

Maura embraces her new journey, but nothing about life as a woman is easy; Sarah introduces her husband to her ex-girlfriend Tammy; Josh pays a visit to his ex-babysitter, Rita; Ali gets closer to her trainer.

Maura moves out of the family house and into a lively new apartment complex, just as Sarah needs a new home after dismantling her perfect life; Josh has to reconsider his sudden vision of starting a family; Ali finds some new boundaries to cross.

Maura finally comes out to Ali, and they join Sarah on a field trip to the mall, where they all get rude lessons in womanhood; Josh is forced to confront his past, thanks to questions from Syd about his longtime relationship with Rita.

After Shelly's husband Ed goes missing, Sarah, Josh and Ali set out to find him; Ali can no longer keep Maura's secret from Josh, which sends him into a tailspin; Maura runs into a Pfefferman family friend and takes a stand for her new identity.

As they struggle to come to terms with Maura, Josh looks for answers from a rabbi named Raquel; Ali looks for answers in a gender studies class with Syd; Sarah is left to answer questions from her own kids, who meet Maura for the first time.