In 2045, the Major and her team work as mercenaries defending a gated town from outlaws; Togusa takes a call.

Armed by a wealthy patron, the Nomads attack Section 9 with AI drones; Togusa accepts a mission from Japan's peace-seeking prime minister.

As Togusa dives into cyberspace to track his former team members, the group is detained by an enigmatic American organization seeking to employ them.

While researching the team's disappearance and John Smith, Togusa takes a risk; the GHOST members question the nature of their mission.

Aramaki sets off after Kusanagi in a race against time; GHOST members begin their assignment, but Huge's cybernetic security forces them to alter their plans.

Following the Section 9 reunion, Kusanagi and her colleagues learn about the "post-humans," a previously unknown threat to humankind.