Meet Dr. Hank Lawson -- young, brilliant, and recently fired from his ER in Brooklyn for all the wrong reasons. Through a twist of fate, he now finds himself the newest "concierge doctor" in the Hamptons. Providing round-the-clock house calls to the community's rich and famous might be lucrative, but it's not without its challenges and frustrations. Along with his social-climbing brother Evan, faithful physician assistant Divya, and the beautiful local hospital administrator Jill, Hank must adapt to this strange new world of privilege and power, while struggling to find a way to do well and do good at the same time.

Hank, Evan, Jill, and Divya attend a retirement party ... for a 27 year-old. The retiree, Tess, a ballerina, is thrilled when Evan expands her culinary horizons by feeding her hot dogs, Slurpees, and other foods she's had to give up to maintain her dancer's physique, but loses consciousness after a few of these junk-food laden meals. Hank discovers she may have a potentially fatal heart condition. Meanwhile, Hank also cares for Jim, a fisherman with Hepatitis C, pro bono. A vulnerable -- and less than sober -- Jill also exposes some of her feelings to Hank after funding for her free clinic falls through.

Hank and Divya are called to the home of a wealthy U.S. senator, whose pushy wife Lilly Everett asks them to perform a discreet "executive physical" on their teenage son Kendrick, who will be Notre Dame's starting quarterback in the fall. Hank gives Kendrick a clean bill of health, but soon Kendrick's vision mysteriously goes blurry, his speech becomes slurred, and he loses consciousness -- and he eventually slips into respiratory arrest. Hank has also been treating, pro bono, a young -- and flat broke -- professional dog-walker, Benny, with a bite on his hand that becomes dangerously infected. Evan, meanwhile, has been busy trying to drum up more female HankMed clients by convincing numerous young women to attend a party the next day at the Shadow Pond grotto, but things don't go as smoothly as planned. Evan's efforts aren't entirely for naught however, as he also helps set up Hank and Jill on their first official date.

When Allison Moore, the owner/head chef of a trendy Hamptons restaurant suffers a stroke, Hank attempts to save her from potential long-term damage, but she goes missing before treatment is administered. Meanwhile, Evan and Divya attempt to define their roles in HankMed. After deciding to take their relationship slowly, Hank and Jill have brunch -- on what would have been Hank's wedding day.

Just as Hank and Jill's relationship is beginning to blossom, he and Evan take a weekend-long assignment -- as doctor and nanny, respectively -- with the wealthy Grant family during a gathering on their technology-free private island. Once there, Hank learns that one of the Grant women is far along in her pregnancy and wants to give birth on the island, despite Hank's reservations. Evan, meanwhile, butts heads with one of the teenage Grant boys, while Jill, back on the mainland, wrestles with hospital politics and her feelings for Hank.

Hank quarantines guests at a "bark mitzvah" after some come down with a serious disease, which causes him and Jill to debate whether or not to call County Health. Meanwhile, Evan makes a startling discovery about Divya's romantic life, while Jill attempts to keep her relationship with Hank out of the public eye.