The Guerrero Brothers are back after the bloody events of Season 1. Meanwhile, Inspector Marquez continues her crusade against the Guerrero brothers and will not stop until she sees them behind bars.

After coming out alive from his confrontation with the Colombians and misleading the police, Daniel returns to the neighborhood and puts Clemente’s fragile tranquillity at risk. Tomás sees his window closing and manages a plan to flee with his family.

Tomás' plan to protect his family fails and his wife and daughter end up in police custody. Tomás finds a way to escape from the company of his brother Daniel. Marquez begins a chase to hunt them down and will not stop at nothing until she catches them.

Daniel and Tomás continue with their desperate escape, without resources, and they will cross Spain by themselves. In Madrid, Clemente has managed to survive, but ends up being alone, without his brothers and without Lorena.

Marquez and Barbara follow the Guerrero brothers to the Portuguese coast where they have everything ready to capture them. Daniel and Tomás have organized their escape in a boat, but things do not go as planned.

Daniel, after fleeing from the Police in Oporto, does not take the Ship towards a new life and decides to return to his old Neighborhood. Tomás is wounded and is taken to Madrid.