With the changing of West Virginia Law, making and selling Moonshine has become legal and a big city Liquor Executive has been approaching members of the infamous Hatfield and McCoy clans looking to launch a new Moonshine Brand. Meanwhile, kin of Devil Anse Hatfield and Randall McCoy, are still squabbling after 150 years. Mark Hatfield and Jim McCoy get into a little tussle about who's moonshine is stronger and decide to settle the score by racing classic cars powered by their own brews.

The Hatfields and McCoys are in agreement for a change...they want nothing to do with each other or that big city liquor investor. Each family has decided to go out on their own and make their own legal moonshine. Problem is they still need to find the money to make it happen and of course make more of their product. Meanwhile, Jim McCoy is having some trouble with his lead foot mamma. Mama Irene is speeding around town in her Mustang and getting in trouble with the law.

Scotty May Hatfield and Mickey McCoy join forces and are determined to get their families together to make this Moonshine deal happen with big liquor exec Monsell. If only Mark Hatfield and Jim McCoy can keep from fighting again. Meanwhile, James McCoy's has decided to test his family's DNA for a rage gene as his latest science experiment.

Jim McCoy and Mark Hatfield come to terms with liquor investor Monsell for a HatField & McCoy White Lightning. With the deal made, money advances given and promises made...Mark Hatfield and Jim McCoy now need to come through with the ancestral waters and a location for their Distillery before they can make one drop of the Hatfield & McCoy Moonshine.

With the lease on the building already signed, Jim McCoy and Mark Hatfield have no choice but to start demolition on the new Hatfield and McCoy Distillery. Meanwhile, Jim and Mark entrust Scotty May to build the industrial sized still they will need to start makin' Moonshine.