Knob Haven High School is in financial trouble, and Acting Principal Sue Sezno must win the upcoming football game to gain alumni donations or face firing a faculty member. Meanwhile, a scandal erupts when pills confiscated from a student's locker becomes a part of Vice Principal Stuart Proszakian’s daily diet.

To celebrate the first day of spring, Miracle distributes flowers (at least she thinks so) to the staff. The flowers turn out to be hemlock, and Andrew winds up in a coma. Larry's pragmatism causes Miracle to lose her hippy-dippy spirituality. As a result, Miracle becomes despondent, and it's up to Larry to help her regain her faith. Meanwhile, Helen's grudge against Sue puts the school's spring fundraiser in jeopardy.

When Knob Haven High School has a chance to become a "distinguished school," Larry volunteers to give a speech to the school board in hopes of impressing Miracle. All looks good for Larry until a video of Ennis surfaces online and Principal Sezno replaces him. Meanwhile, Willard volunteers to teach Driver's Ed in hopes of overcoming his fear of driving.

In an effort to impress the PTA, the faculty and staff of Knob Haven High School throw a party at Huey Lewis' house! In true John Hughes fashion, the teachers decide to shake it up: Larry tries to get Miracle's attention with his "interesting" date, Helen attempts to reinvent herself, Andrew finds his true identity and Willard goes on a booze run in a DeLorean that takes him across town and the time-space continuum in this homage to the 1980s.

Stuart is named editor of the student newspaper and tries to boost sales by printing salacious stories. When Larry uncovers some information on Miracle that gets her fired, the two go on the lam. Meanwhile, Sue attempts to hide her own juicy story.

When Ennis offers to give the staff a course on dating to help their relationship issues, Larry objects to his methods and ends up meeting a mysterious lady from Ennis' past. Meanwhile, Miracle reveals an underground club to Sue that may end up being deadly for both of them.